Arthritis and Joint Preservation

Identifying molecular and mechanical pathways that lead to joint degeneration and quantifying the abilities of surgery to intervene.


Research Team and Focus

Larry Bonassar, PhD, Daljit S. and Elaine Sarkaria Professor in Biomedical Engineering
Cartilage biomechanics – mechanical testing, lubrication, microelastography; Tissue engineering/regenerative medicine – biomaterials, materials processing, 3D printing/additive manufacturing; Tissue biomanufacturing – scalable technologies for reproducible production of engineered tissues

Nikolas Bouklas, MD, Assistant Professor
Computational mechanics – Mechanics of soft materials, Modeling of damage and fracture mechanics in highly nonlinear materials, Mechanotransduction – Repair and structural reconfiguration in engineered contractile microtissues

Brian P. Chalmers, MD, Assistant Attending Orthopedic Surgeon
zprimary hip and knee replacement, partial knee replacement, complex and revision hip and knee replacement, and periprosthetic fractures and infections

Itai Cohen, PhD, Professor, Department of Physics
Development of new experimental techniques, analysis tools, and theoretical models for studying and modeling the physics of interactions between colloidal particles, polymeric strands, neurons, and individuals

Peter Fabricant, MD, Assisant Attending/Professor of Pediatric Orthopedics
Pediatric and adolescent orthopedic surgery: sports medicine and trauma surgery of the knee, shoulder, elbow, and ankle

Lisa Fortier, DVM, PhD, Professor of Surgery
Regenerative medicine for OA and tendinopathy,immunology of OA, large animal surgeries

Andreas Gomoll, MD, Associate Attending/Professor of Orthopedic Surgery
Reconstruction of knee injuries, such as ACL tears, meniscus and cartilage defects.

Carl Imhauser, PhD, Associate Scientist
Mechanics of human joints focusing on knee, Joint stability and ligament (ACL) mechanics, Clinical and translational research, Physical testing of knee joints (cadavers and patients), Modeling and simulation focusing on multibody dynamics

Matthew Koff, PhD, Associate Scientist
Musculoskeletal magnetic resonance imaging, human subjects research and preclinical models

Suzanne Maher, PhD, Senior Scientist
Knee joint mechanics, kinematics, physiological inputs to bioreactors, mechanical factors influencing development of OA after injury/ surgery, product development/ commercialization & pre-clinical testing – materials cartilage, meniscus

Miguel Otero, PhD, Assistant Scientist
Cartilage biology, analyses of synovium/adipose tissue, genomics/epigenomics approaches, In vitro systems, animal models of OA, transcription

Anil Ranawat, MD, Associate Attending/Professor of Orthopedic Surgery
Hip and knee arthroscopy, Femoroacetabular impingement surgery (FAI), Labral Tears, Avascular necrosis, Complex and Tibial Osteotomies, Robotic partial knee replacement

Heidi Reesink, VMD, PhD, DACVS-LA, Assistant Professor of Equine Health
Experimental and naturally occurring animal OA models – rat, horse, dog; Recombinant lubricin production and characterization of lubricin, HA, and other synovial fluid glycans

Sabrina Strickland, MD, Associate Attending/Professor of Orthopedic Surgery
Patellofemoral cartilage defects, patellofemoral instability, ligament injuries of the knee and shoulder